A Case of Myxofibrosarcoma in an Unusual Thoracic Location

Authors

Kavitha Gopalratnam, Bridgeport Hospital, Yale New Haven Health, Bridgeport, Conn., USA.Follow
Jose A. Rodriguez, Bridgeport Hospital, Yale New Haven Health, Bridgeport, Conn., USA.
Kevin A. Woodson, Bridgeport Hospital, Yale New Haven Health, Bridgeport, Conn., USA.Follow
Robert Folman, Yale Cancer Center, New Haven, Conn., USA.

Document Type

Article

Publication Title

Case reports in oncology

Abstract

Myxofibrosarcoma is a soft tissue neoplasm composed of malignant fibroblasts with a myxoid matrix. It is commonly found in patients during their 6th through 8th decades of life with a slight male predominance. Myxofibrosarcomas are classified as low- to high-grade tumors that are differentiated by hypercellularity, variation of mitotic activity and degree of necrosis. The most common sites are the extremities (77%) and trunk (12%), with the retroperitoneum and mediastinum being very rare. In this case report, we describe a patient presenting with myxofibrosarcoma of the mediastinum, a rare site for the development of myxofibrosarcoma. This case of primary mediastinal myxofibrosarcoma appears to be only the second described in the English-language literature.

First Page

39

Last Page

44

DOI

10.1159/000442875

Publication Date

1-1-2016

Recommended Citation

Gopalratnam, Kavitha; Rodriguez, Jose A.; Woodson, Kevin A.; and Folman, Robert, "A Case of Myxofibrosarcoma in an Unusual Thoracic Location" (2016). Critical Care. 83.
https://scholar.bridgeporthospital.org/critical_care/83

Identifier

26933417 (pubmed); PMC4748782 (pmc); 10.1159/000442875 (doi); cro-0009-0039 (pii)