Ventricular Tachycardia and Hospital Readmission in Patients Discharged From the Hospital After an Acute Myocardial Infarction

Authors

Vu Hoang Tran, Department of Medicine, UMass Memorial Medical Group, Fitchburg, Massachusetts, USA.
Darleen Lessard, Department of Population and Quantitative Health Sciences, Univeristy of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Jay Parekh, Department of Medicine, Bridgeport Hospital, Yale New Haven Health, New Haven, Connecticut, USA.
Mayra S. Tisminetzky, Department of Medicine, Univeristy of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Joel M. Gore, Department of Medicine, Univeristy of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Jorge Yarzebski, Department of Population and Quantitative Health Sciences, Univeristy of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Edgard Granillo, Department of Population and Quantitative Health Sciences, Univeristy of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Tuyet T. Nguyen, Department of Medicine, College of Health Sciences, Vin University, Hanoi, Vietnam.
Robert Goldberg, Department of Population and Quantitative Health Sciences, Univeristy of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.

Document Type

Article

Publication Title

CJC open

Abstract

BACKGROUND: Although ventricular tachycardia (VT) occurring during hospitalization for an acute myocardial infarction (AMI) increases mortality risk, its relationship with 30-day postdischarge rehospitalization has not been examined. METHODS: Using data from the Worcester Heart Attack Study, we examined the association between early (during the first 48 hours of admission) and late (after 48 hours from admission) VT with 30-day postdischarge all-cause and cardiovascular disease (CVD)-related rehospitalization while analytically controlling for several demographic and clinical factors. RESULTS: The study population consisted of 3534 patients who were hospitalized with an AMI between 2005 and 2015 (average age, 67.2 years; 40.7% women); VT occurred in 452 patients (13.7%), with the majority of instances (81.2%) occurring within 48 hours of admission. The 30-day all-cause rehospitalization rate was 17.3%, with 70.9% of the hospitalizations related to CVD. The odds of rehospitalization were 1.63 times (95% confidence interval [CI] = 0.99-2.69) and 1.12 times (95% CI = 0.83-1.51) higher for patients with AMI who developed late VT and early VT, respectively, compared to patients who did not develop VT. The risk of rehospitalization among patients with late VT was higher (odds ratio = 2.22 (95% CI = 0.79-6.26) in those with ST-segment-elevation AMI, compared to those with non-ST-segment-elevation AMI (odds ratio = 1.45 (95% CI = 0.81-2.57); early VT was not associated with rehospitalization in patients with either AMI subtype. No significant association was present between the occurrence of VT and CVD-related rehospitalization. CONCLUSIONS: Patients who develop late VT may experience a higher risk of 30-day rehospitalization following hospital discharge for AMI, especially among those with ST-segment-elevation AMI. Larger studies are needed to confirm our findings.

First Page

781

Last Page

789

DOI

10.1016/j.cjco.2024.02.001

Publication Date

6-1-2024

Recommended Citation

Tran, Vu Hoang; Lessard, Darleen; Parekh, Jay; Tisminetzky, Mayra S.; Gore, Joel M.; Yarzebski, Jorge; Granillo, Edgard; Nguyen, Tuyet T.; and Goldberg, Robert, "Ventricular Tachycardia and Hospital Readmission in Patients Discharged From the Hospital After an Acute Myocardial Infarction" (2024). Internal Medicine. 194.
https://scholar.bridgeporthospital.org/internal_medicine/194

Identifier

39022163 (pubmed); PMC11250869 (pmc); 10.1016/j.cjco.2024.02.001 (doi); S2589-790X(24)00050-7 (pii)