Lutheran b blood group alloimmunization: case series and literature review

Document Type

Article

Publication Title

Connecticut medicine

Abstract

The Lutheran b blood antigen is a high prevalence antigen occurring in 99.8% of Caucasians. Consequently, antibody formation against Lutheran b is very rare. While this antibody can cause hemolytic reactions in adults, there is limited clinical information on its effects on the fetus and newborn. As a high prevalence antigen, it may be difficult to obtain Lutheran b-negative blood for possible maternal transfusion. We describe two cases of pregnancy complicated by Lutheran b alloimmunization. These cases highlight the potential fetal and maternal complications associated with this antibody and we review options to maximize perinatal outcome.

First Page

363

Last Page

5

Publication Date

1-1-2006

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