Atypical posterior reversible encephalopathy syndrome in a case of thrombotic thrombocytopenic purpura with Sjogren's syndrome
Document Type
Article
Publication Title
Radiology case reports
Abstract
Thrombotic thrombocytopenic purpura (TTP) is a rare hematologic disorder characterized by thrombotic microangiopathy. Neurologic symptoms are frequently seen in its presentation and the most common finding on neuroimaging of TTP is posterior reversible encephalopathy syndrome (PRES). Acute strokes, hemorrhages and atypical PRES are uncommonly seen. Our case reports the clinical and imaging details of a young male patient with TTP and Sjogren's syndrome, who made a complete recovery after aggressive plasmapheresis and immunosuppressive therapy with resolution of the imaging findings of PRES on follow up brain MR imaging. We briefly review the literature for the spectrum of imaging findings that can be seen on brain MRI with TTP.
First Page
1552
Last Page
1556
DOI
10.1016/j.radcr.2021.03.035
Publication Date
6-1-2021
Recommended Citation
Hegde, Rahul; Ismail, Rasha; Vegunta, Aishwariya; Megahed, Ayah; Sharma, Pranav; and Rosovsky, Mark, "Atypical posterior reversible encephalopathy syndrome in a case of thrombotic thrombocytopenic purpura with Sjogren's syndrome" (2021). Radiology. 121.
https://scholar.bridgeporthospital.org/radiology/121
Identifier
33981376 (pubmed); PMC8082195 (pmc); 10.1016/j.radcr.2021.03.035 (doi); S1930-0433(21)00174-6 (pii)