Advanced imaging for pre- and post-operative evaluation of tetralogy of Fallot

Authors

Mohammad H. Jalili, Department of Radiology, Yale New Haven Health, Bridgeport Hospital, 267 Grant St, Bridgeport, CT 06610, USA.
Alex Chung, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suit 3371, Los Angeles, CA 90095, USA.
Daniel Bradley, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suit 3371, Los Angeles, CA 90095, USA.
Cameron Hassani, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suit 3371, Los Angeles, CA 90095, USA.
Ashley E. Prosper, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suit 3371, Los Angeles, CA 90095, USA.
J Paul Finn, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suit 3371, Los Angeles, CA 90095, USA.
Arash Bedayat, Department of Radiological Sciences, David Geffen School of Medicine at UCLA, 10945 Le Conte Ave, Suit 3371, Los Angeles, CA 90095, USA. Electronic address: ABedayat@mednet.UCLA.edu.

Document Type

Article

Publication Title

Clinical imaging

Abstract

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease and imaging plays a key role in diagnosis, pre-operative planning and follow up, with MRI as the gold standard for imaging in these patients despite echocardiography being more widely available. While static MRI sequences are suitable for evaluation of anatomical structures, dynamic imaging is required for volume and flow measurements through valves, chambers, and surgical conduits. Newer techniques with 4D data acquisitions allow for feasible 2D cine reconstruction in desired planes. Ferumoxytol, a blood pool contrast agent with long intravascular half-life, facilitates acquisition of 4D flow and 4D MUSIC (multiphase, steady-state imaging with contrast) sequences, eliminating need for repeated contrast administrations. In this article we review conglomerate of TOF anomalies, their historical and current surgical managements with respective devices, as well as cutting-edge MRI techniques for their evaluation.

First Page

110432

DOI

10.1016/j.clinimag.2025.110432

Publication Date

2-12-2025

Recommended Citation

Jalili, Mohammad H.; Chung, Alex; Bradley, Daniel; Hassani, Cameron; Prosper, Ashley E.; Finn, J Paul; and Bedayat, Arash, "Advanced imaging for pre- and post-operative evaluation of tetralogy of Fallot" (2025). Radiology. 126.
https://scholar.bridgeporthospital.org/radiology/126

Identifier

39954316 (pubmed); 10.1016/j.clinimag.2025.110432 (doi); S0899-7071(25)00032-4 (pii)