Toxins in Brain! Magnetic Resonance (MR) Imaging of Toxic Leukoencephalopathy - A Pictorial Essay

Authors

Yogesh Kumar, Department of Radiology, Yale New Haven Health System at Bridgeport Hospital, Bridgeport, CT, U.S.A.Follow
Douglas Drumsta, Department of Imaging Sciences, University of Rochester Medical Centre, Rochester NY, U.S.A.
Manisha Mangla, State University of New York (SUNY) Upstate Medical University, Syracuse, NY, U.S.A.Follow
Nishant Gupta, Department of Radiology, St. Vincent's Medical Center, Bridgeport, CT, U.S.A.Follow
Kusum Hooda, Department of Radiology, Yale New Haven Health System at Bridgeport Hospital, Bridgeport, CT, U.S.A.Follow
Jeevak Almast, Department of Imaging Sciences, University of Rochester Medical Centre, Rochester NY, U.S.A.
Rajiv Mangla, Department of Radiology, State University of New York (SUNY) Upstate Medical University, Syracuse, NY, U.S.A.Follow

Document Type

Article

Publication Title

Polish journal of radiology

Abstract

Toxic leukoencephalopathy results from damage to the white matter caused by various toxins. It manifests itself as white matter signal abnormalities with or without the presence of restricted diffusion. These changes are often reversible if the insulting agent is removed early, with the exception of posthypoxic leukoencephalopathy that can manifest itself 1-2 weeks after the initial insult. However, many other potential causes of white matter signal abnormalities can mimic the changes of toxic leukoencephalopathy. Thus, familiarity with the causes, clinical presentation and particularly imaging findings of toxic leukoencephalopathy is critical for early treatment and improved prognosis. The purpose of this pictorial essay is to familiarize the reader with the various causes of toxic leukoencephalopathy along with its differential diagnoses and mimics.

First Page

311

Last Page

319

DOI

10.12659/PJR.901791

Publication Date

1-1-2017

Recommended Citation

Kumar, Yogesh; Drumsta, Douglas; Mangla, Manisha; Gupta, Nishant; Hooda, Kusum; Almast, Jeevak; and Mangla, Rajiv, "Toxins in Brain! Magnetic Resonance (MR) Imaging of Toxic Leukoencephalopathy - A Pictorial Essay" (2017). Radiology. 99.
https://scholar.bridgeporthospital.org/radiology/99

Identifier

28656068 (pubmed); PMC5478246 (pmc); 10.12659/PJR.901791 (doi); 901791 (pii)