New onset squamous cell carcinoma in previous split-thickness skin graft donor site

Authors

Vincent J. Noori, Department of Surgery, Maine Medical Center, Portland, ME 04102, United States; Department of Surgery, Bridgeport Medical Center, Bridgeport, CT 06610, United States.
Kanika Trehan, Department of Surgery, Maine Medical Center, Portland, ME 04102, United States; Department of Surgery, Bridgeport Medical Center, Bridgeport, CT 06610, United States.Follow
Alisa Savetamal, Department of Surgery, Maine Medical Center, Portland, ME 04102, United States; Department of Surgery, Bridgeport Medical Center, Bridgeport, CT 06610, United States.Follow
Damien W. Carter, Department of Surgery, Maine Medical Center, Portland, ME 04102, United States; Department of Surgery, Bridgeport Medical Center, Bridgeport, CT 06610, United States. Electronic address: dcarter@mmc.org.Follow

Document Type

Article

Publication Title

International journal of surgery (London, England)

Abstract

INTRODUCTION: Marjolin' s ulcer, an aggressive ulcerating squamous cell carcinoma, is a well-known phenomenon that occurs in chronically inflamed or scarred tissue; however, squamous cell carcinoma arising in the acute setting after tissue trauma - specifically autograft donor harvest sites for burns - is a rare, but notable event. METHODS: This case series describes three instances of squamous cell carcinoma diagnosed in split-thickness skin graft donor sites in the immediate post-operative period. Charts were reviewed in detail after at least 9 months follow-up from identification of the tumor. Detailed descriptions of each case are included. A discussion of the literature on this rare entity is included as well. RESULTS: In the three cases discussed, all were characterized clinically as painful masses arising in a recently healed donor site. Two were managed surgically with adherence to oncologic principals. One lesion regressed or fell off spontaneously. With at least 9 months follow-up, there was no evidence of recurrence. CONCLUSIONS: Very few cases of acute neoplasm in donor sites have been described in the literature. Presently, there is no dominant theory as to how these lesions arise; however, this is an entity that burn care providers, world wide should be aware of, with a low threshold for oncologic evaluation if suspected.

First Page

16

Last Page

19

DOI

10.1016/j.ijsu.2018.01.047

Publication Date

4-1-2018

Recommended Citation

Noori, Vincent J.; Trehan, Kanika; Savetamal, Alisa; and Carter, Damien W., "New onset squamous cell carcinoma in previous split-thickness skin graft donor site" (2018). Surgery. 147.
https://scholar.bridgeporthospital.org/surgery/147

Identifier

29438815 (pubmed); 10.1016/j.ijsu.2018.01.047 (doi); S1743-9191(18)30526-0 (pii)