American Burn Association Clinical Practice Guidelines on Burn Shock Resuscitation

Authors

Robert Cartotto, Department of Surgery, Ross Tilley Burn Centre, Sunnybrook Heath Sciences Centre, University of Toronto, Canada.Follow
Laura S. Johnson, Department of Surgery, Walter L. Ingram Burn Center, Grady Memorial Hospital, Emory University, Atlanta, GAUSA.Follow
Alisa Savetamal, Department of Surgery, Connecticut Burn Center, Bridgeport Hospital, Bridgeport, CT, USA.Follow
David Greenhalgh, Shriners Hospital for Children, Northern California, Sacramento, CA, USA.Follow
John C. Kubasiak, Department of Surgery, Loyola University Medical Center, Maywood, IL, USA.Follow
Tam N. Pham, Department of Surgery, University of Washington Regional Burn Center, Harborview Medical Center, Seattle, WA, USA.
Julie A. Rizzo, Department of Trauma, Brooke Army Medical Center, Fort Sam Houston, San Antonio, TX, USA.Follow
Soman Sen, Department of Surgery, Division of Burn Surgery, University of California, Davis, CA, USA.Follow
Emilia Main, Sunnybrook Health Sciences Centre, Toronto, Canada.Follow

Document Type

Article

Publication Title

Journal of burn care & research : official publication of the American Burn Association

Abstract

This Clinical Practice Guideline (CPG) addresses the topic of acute fluid resuscitation during the first 48 hours following a burn injury for adults with burns ≥20% of the total body surface area (%TBSA). The listed authors formed an investigation panel and developed clinically relevant PICO (Population, Intervention, Comparator, Outcome) questions. A systematic literature search returned 5978 titles related to this topic and after 3 levels of screening, 24 studies met criteria to address the PICO questions and were critically reviewed. We recommend that clinicians consider the use of human albumin solution, especially in patients with larger burns, to lower resuscitation volumes and improve urine output. We recommend initiating resuscitation based on providing 2 mL/kg/% TBSA burn in order to reduce resuscitation fluid volumes. We recommend selective monitoring of intra-abdominal and intraocular pressure during burn shock resuscitation. We make a weak recommendation for clinicians to consider the use of computer decision support software to guide fluid titration and lower resuscitation fluid volumes. We do not recommend the use of transpulmonary thermodilution-derived variables to guide burn shock resuscitation. We are unable to make any recommendations on the use of high-dose vitamin C (ascorbic acid), fresh frozen plasma (FFP), early continuous renal replacement therapy, or vasopressors as adjuncts during acute burn shock resuscitation. Mortality is an important outcome in burn shock resuscitation, but it was not formally included as a PICO outcome because the available scientific literature is missing studies of sufficient population size and quality to allow us to confidently make recommendations related to the outcome of survival at this time.

First Page

565

Last Page

589

DOI

10.1093/jbcr/irad125

Publication Date

5-6-2024

Recommended Citation

Cartotto, Robert; Johnson, Laura S.; Savetamal, Alisa; Greenhalgh, David; Kubasiak, John C.; Pham, Tam N.; Rizzo, Julie A.; Sen, Soman; and Main, Emilia, "American Burn Association Clinical Practice Guidelines on Burn Shock Resuscitation" (2024). Surgery. 5.
https://scholar.bridgeporthospital.org/surgery/5