IMPACT OF CIRRHOSIS ON IN-HOSPITAL OUTCOMES IN CARDIOGENIC SHOCK PATIENTS WITH TEMPORARY MECHANICAL CIRCULATORY SUPPORT: INSIGHTS FROM NATIONAL INPATIENT SAMPLE (2016-2020)

Authors

Bekure B. Siraw, School of Public Health, University of California, 1279 Webster St. San Francisco, Berkeley, CA, 94115, USA. bekure_siraw@berkeley.edu.
Didien Meyahnwi MD, Yale New Haven Health/Bridgeport Hospital
Yordanos T. Tafesse, Biological Sciences, The University of Chicago Medicine, Chicago, USA.
Thaio Nguyen
Hemraj Paudel
Mohammed Haroun
Gabriel Valagni
Mouaz Oudih
Juveriya Yasmeen, Internal Medicine, Ascension Saint Joseph Hospital, Chicago, USA.
Khalid Hussein
Satish Bastola
ashok Kumar

Document Type

Conference Proceeding

Publication Title

Journal of the American College of Cardiology

Abstract

Background

Cirrhosis complicates outcomes of cardiovascular conditions like cardiogenic shock (CS). Temporary mechanical circulatory support (tMCS) devices—such as intra-aortic balloon pumps (IABP), percutaneous ventricular assist devices (pVAD), and extracorporeal membrane oxygenation (ECMO)—are vital for CS management. Cirrhosis may affect the efficacy and safety of these interventions.

Methods

Using National Inpatient Sample data from 2016 to 2020, we identified CS admissions and tMCS use via ICD-10 codes. Cirrhosis admissions were also identified using ICD-10 codes. A 1:1 nearest-neighbor propensity score matching was conducted to match cirrhosis and non-cirrhosis admissions. In-hospital mortality was the primary outcome, while complications, length of stay, and hospitalization costs were secondary.

Results

The sample included 3,330 patients, evenly split between groups. The mean age was 62.6 years (SD 11.1), with 71.8% male. Ethnic distribution was 68.9% White, 13.4% Hispanic, and 9% Black. IABP (73.2%) was the most used tMCS, with an overall mortality rate of 33.9%. The cirrhosis group had higher mortality (39.6% vs. 28.3%, p<0.001) and greater odds of infections and bleeding but lower odds of thrombosis. No differences were found in the rest of the complications, length of stay, or cost of hospitalization.

Conclusion

Cirrhosis significantly raises in-hospital mortality and complications in CS patients using tMCS, underscoring the need for tailored clinical management.

Publication Date

4-1-2025

Comments

Poster Contributions South Hall Saturday, March 29, 2025, 3:30 p.m.-4:30 p.m. Session Title: Featured Fields 05 Abstract Category: 54. Featured Fields: Critical Care Cardiology Presentation Number: 1105-48

Recommended Citation

Siraw, Bekure B.; Meyahnwi, Didien MD; Tafesse, Yordanos T.; Nguyen, Thaio; Paudel, Hemraj; Haroun, Mohammed; Valagni, Gabriel; Oudih, Mouaz; Yasmeen, Juveriya; Hussein, Khalid; Bastola, Satish; and Kumar, ashok, "IMPACT OF CIRRHOSIS ON IN-HOSPITAL OUTCOMES IN CARDIOGENIC SHOCK PATIENTS WITH TEMPORARY MECHANICAL CIRCULATORY SUPPORT: INSIGHTS FROM NATIONAL INPATIENT SAMPLE (2016-2020)" (2025). Abstracts. 16.
https://scholar.bridgeporthospital.org/abstract_presentations/16